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low virulence control strain atcc 700603  (ATCC)


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    ATCC low virulence control strain atcc 700603
    Low Virulence Control Strain Atcc 700603, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 4202 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/virulence+strain+atcc+700603/pm41728941-166-8-11?v=ATCC
    Average 99 stars, based on 4202 article reviews
    low virulence control strain atcc 700603 - by Bioz Stars, 2026-07
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    low virulence control strain atcc 700603  (ATCC)
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    virulence reference strain atcc 700603  (ATCC)
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    virulence strain k pneumoniae atcc 700603  (ATCC)
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    The mucoviscosity (A) , capsule quantification (B) , and serum resistance (C) of ST627-KL8 strains. (A) Mucoviscosity in three ST627-KL8 clinical strains, K. pneumoniae ATCC 43816 and K. pneumoniae ATCC 700603. The mucoviscosity of strains was determined by a semi-quantitative measurement. (B) Capsule uronic acid production in three ST627-KL8 clinical strains, K. pneumoniae ATCC 43816 and K. pneumoniae ATCC 700603. (C) The resistance of strains against human serum. The serum killing assays were performed by incubating three ST627-KL8 isolates, K. pneumoniae ATCC 43816 and K. pneumoniae ATCC 700603, with human serum for 1, 2, or 3 h at 37°C. Data are presented as mean ± SD derived from three separate experiments. One-way ANOVA with Dunnett’s test was used to analyze data, **** p < 0.0001. For panel (C) , **** p < 0.0001 and *** p < 0.001 indicated ST627-KL8 versus K. pneumoniae ATCC 43816, #### p < 0.0001 and ### p < 0.001 for ST627-KL8 versus K. pneumoniae ATCC 700603.
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    low virulence k pneumoniae atcc 700603 strain  (ATCC)
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    The mucoviscosity (A) , capsule quantification (B) , and serum resistance (C) of ST627-KL8 strains. (A) Mucoviscosity in three ST627-KL8 clinical strains, K. pneumoniae ATCC 43816 and K. pneumoniae ATCC 700603. The mucoviscosity of strains was determined by a semi-quantitative measurement. (B) Capsule uronic acid production in three ST627-KL8 clinical strains, K. pneumoniae ATCC 43816 and K. pneumoniae ATCC 700603. (C) The resistance of strains against human serum. The serum killing assays were performed by incubating three ST627-KL8 isolates, K. pneumoniae ATCC 43816 and K. pneumoniae ATCC 700603, with human serum for 1, 2, or 3 h at 37°C. Data are presented as mean ± SD derived from three separate experiments. One-way ANOVA with Dunnett’s test was used to analyze data, **** p < 0.0001. For panel (C) , **** p < 0.0001 and *** p < 0.001 indicated ST627-KL8 versus K. pneumoniae ATCC 43816, #### p < 0.0001 and ### p < 0.001 for ST627-KL8 versus K. pneumoniae ATCC 700603.
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    virulence strain atcc 700603  (ATCC)
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    ATCC virulence strain atcc 700603
    Virulence assessment of the 46 CR-hvKP clinical isolates using the Galleria mellonella infection model. Survival curves of the larvae infected with CR-hvKP strains are shown in comparison with the high-virulence control strain NTUH-K2044, low-virulence control strain ATCC 700603, and PBS control. Statistical significance was determined by the log-rank (Mantel-Cox) test.
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    The mucoviscosity (A) , capsule quantification (B) , and serum resistance (C) of ST627-KL8 strains. (A) Mucoviscosity in three ST627-KL8 clinical strains, K. pneumoniae ATCC 43816 and K. pneumoniae ATCC 700603. The mucoviscosity of strains was determined by a semi-quantitative measurement. (B) Capsule uronic acid production in three ST627-KL8 clinical strains, K. pneumoniae ATCC 43816 and K. pneumoniae ATCC 700603. (C) The resistance of strains against human serum. The serum killing assays were performed by incubating three ST627-KL8 isolates, K. pneumoniae ATCC 43816 and K. pneumoniae ATCC 700603, with human serum for 1, 2, or 3 h at 37°C. Data are presented as mean ± SD derived from three separate experiments. One-way ANOVA with Dunnett’s test was used to analyze data, **** p < 0.0001. For panel (C) , **** p < 0.0001 and *** p < 0.001 indicated ST627-KL8 versus K. pneumoniae ATCC 43816, #### p < 0.0001 and ### p < 0.001 for ST627-KL8 versus K. pneumoniae ATCC 700603.

    Journal: Frontiers in Microbiology

    Article Title: Emergence and characterization of a novel ST627-KL8 carbapenem-resistant Klebsiella pneumoniae lineage associated with ICU transmission in a tertiary hospital, China

    doi: 10.3389/fmicb.2025.1723336

    Figure Lengend Snippet: The mucoviscosity (A) , capsule quantification (B) , and serum resistance (C) of ST627-KL8 strains. (A) Mucoviscosity in three ST627-KL8 clinical strains, K. pneumoniae ATCC 43816 and K. pneumoniae ATCC 700603. The mucoviscosity of strains was determined by a semi-quantitative measurement. (B) Capsule uronic acid production in three ST627-KL8 clinical strains, K. pneumoniae ATCC 43816 and K. pneumoniae ATCC 700603. (C) The resistance of strains against human serum. The serum killing assays were performed by incubating three ST627-KL8 isolates, K. pneumoniae ATCC 43816 and K. pneumoniae ATCC 700603, with human serum for 1, 2, or 3 h at 37°C. Data are presented as mean ± SD derived from three separate experiments. One-way ANOVA with Dunnett’s test was used to analyze data, **** p < 0.0001. For panel (C) , **** p < 0.0001 and *** p < 0.001 indicated ST627-KL8 versus K. pneumoniae ATCC 43816, #### p < 0.0001 and ### p < 0.001 for ST627-KL8 versus K. pneumoniae ATCC 700603.

    Article Snippet: The low-virulence strain K. pneumoniae ATCC 700603 exhibited a high survival rate of 96.7% (29/30 larvae), statistically comparable to that of the PBS control group (96.7%, 29/30).

    Techniques: Derivative Assay

    Virulence assessment of three ST627-KL8 CRKP isolates in the G. mellonella infection model. Larvae were injected with PBS (negative control), reference strains K. pneumoniae ATCC 700603 (low-virulence control), K. pneumoniae ATCC 43816 (hypervirulent control), and three ST627-KL8 CRKP isolates (ZJG29565, ZJG30140, ZJG30146) separately. Survival was monitored over time ( n = 30 larvae per group). Survival curves were generated using the Kaplan–Meier method, and statistical significance between groups was determined by the Log-rank test. Data are representative of three independent experiments.

    Journal: Frontiers in Microbiology

    Article Title: Emergence and characterization of a novel ST627-KL8 carbapenem-resistant Klebsiella pneumoniae lineage associated with ICU transmission in a tertiary hospital, China

    doi: 10.3389/fmicb.2025.1723336

    Figure Lengend Snippet: Virulence assessment of three ST627-KL8 CRKP isolates in the G. mellonella infection model. Larvae were injected with PBS (negative control), reference strains K. pneumoniae ATCC 700603 (low-virulence control), K. pneumoniae ATCC 43816 (hypervirulent control), and three ST627-KL8 CRKP isolates (ZJG29565, ZJG30140, ZJG30146) separately. Survival was monitored over time ( n = 30 larvae per group). Survival curves were generated using the Kaplan–Meier method, and statistical significance between groups was determined by the Log-rank test. Data are representative of three independent experiments.

    Article Snippet: The low-virulence strain K. pneumoniae ATCC 700603 exhibited a high survival rate of 96.7% (29/30 larvae), statistically comparable to that of the PBS control group (96.7%, 29/30).

    Techniques: Infection, Injection, Negative Control, Control, Generated

    The mucoviscosity (A) , capsule quantification (B) , and serum resistance (C) of ST627-KL8 strains. (A) Mucoviscosity in three ST627-KL8 clinical strains, K. pneumoniae ATCC 43816 and K. pneumoniae ATCC 700603. The mucoviscosity of strains was determined by a semi-quantitative measurement. (B) Capsule uronic acid production in three ST627-KL8 clinical strains, K. pneumoniae ATCC 43816 and K. pneumoniae ATCC 700603. (C) The resistance of strains against human serum. The serum killing assays were performed by incubating three ST627-KL8 isolates, K. pneumoniae ATCC 43816 and K. pneumoniae ATCC 700603, with human serum for 1, 2, or 3 h at 37°C. Data are presented as mean ± SD derived from three separate experiments. One-way ANOVA with Dunnett’s test was used to analyze data, **** p < 0.0001. For panel (C) , **** p < 0.0001 and *** p < 0.001 indicated ST627-KL8 versus K. pneumoniae ATCC 43816, #### p < 0.0001 and ### p < 0.001 for ST627-KL8 versus K. pneumoniae ATCC 700603.

    Journal: Frontiers in Microbiology

    Article Title: Emergence and characterization of a novel ST627-KL8 carbapenem-resistant Klebsiella pneumoniae lineage associated with ICU transmission in a tertiary hospital, China

    doi: 10.3389/fmicb.2025.1723336

    Figure Lengend Snippet: The mucoviscosity (A) , capsule quantification (B) , and serum resistance (C) of ST627-KL8 strains. (A) Mucoviscosity in three ST627-KL8 clinical strains, K. pneumoniae ATCC 43816 and K. pneumoniae ATCC 700603. The mucoviscosity of strains was determined by a semi-quantitative measurement. (B) Capsule uronic acid production in three ST627-KL8 clinical strains, K. pneumoniae ATCC 43816 and K. pneumoniae ATCC 700603. (C) The resistance of strains against human serum. The serum killing assays were performed by incubating three ST627-KL8 isolates, K. pneumoniae ATCC 43816 and K. pneumoniae ATCC 700603, with human serum for 1, 2, or 3 h at 37°C. Data are presented as mean ± SD derived from three separate experiments. One-way ANOVA with Dunnett’s test was used to analyze data, **** p < 0.0001. For panel (C) , **** p < 0.0001 and *** p < 0.001 indicated ST627-KL8 versus K. pneumoniae ATCC 43816, #### p < 0.0001 and ### p < 0.001 for ST627-KL8 versus K. pneumoniae ATCC 700603.

    Article Snippet: In the Galleria mellonella model, ST627-KL8 exhibited intermediate virulence (66.7%–76.7% survival), between the hypervirulent K. pneumoniae ATCC 43816 strain (30.0%) and the low-virulence K. pneumoniae ATCC 700603 strain (96.7%).

    Techniques: Derivative Assay

    Virulence assessment of three ST627-KL8 CRKP isolates in the G. mellonella infection model. Larvae were injected with PBS (negative control), reference strains K. pneumoniae ATCC 700603 (low-virulence control), K. pneumoniae ATCC 43816 (hypervirulent control), and three ST627-KL8 CRKP isolates (ZJG29565, ZJG30140, ZJG30146) separately. Survival was monitored over time ( n = 30 larvae per group). Survival curves were generated using the Kaplan–Meier method, and statistical significance between groups was determined by the Log-rank test. Data are representative of three independent experiments.

    Journal: Frontiers in Microbiology

    Article Title: Emergence and characterization of a novel ST627-KL8 carbapenem-resistant Klebsiella pneumoniae lineage associated with ICU transmission in a tertiary hospital, China

    doi: 10.3389/fmicb.2025.1723336

    Figure Lengend Snippet: Virulence assessment of three ST627-KL8 CRKP isolates in the G. mellonella infection model. Larvae were injected with PBS (negative control), reference strains K. pneumoniae ATCC 700603 (low-virulence control), K. pneumoniae ATCC 43816 (hypervirulent control), and three ST627-KL8 CRKP isolates (ZJG29565, ZJG30140, ZJG30146) separately. Survival was monitored over time ( n = 30 larvae per group). Survival curves were generated using the Kaplan–Meier method, and statistical significance between groups was determined by the Log-rank test. Data are representative of three independent experiments.

    Article Snippet: In the Galleria mellonella model, ST627-KL8 exhibited intermediate virulence (66.7%–76.7% survival), between the hypervirulent K. pneumoniae ATCC 43816 strain (30.0%) and the low-virulence K. pneumoniae ATCC 700603 strain (96.7%).

    Techniques: Infection, Injection, Negative Control, Control, Generated

    Virulence assessment of the 46 CR-hvKP clinical isolates using the Galleria mellonella infection model. Survival curves of the larvae infected with CR-hvKP strains are shown in comparison with the high-virulence control strain NTUH-K2044, low-virulence control strain ATCC 700603, and PBS control. Statistical significance was determined by the log-rank (Mantel-Cox) test.

    Journal: Microbiology Spectrum

    Article Title: Epidemiological and functional insights into iroBCDN loss in ST11 carbapenem-resistant hypervirulent Klebsiella pneumoniae

    doi: 10.1128/spectrum.02479-25

    Figure Lengend Snippet: Virulence assessment of the 46 CR-hvKP clinical isolates using the Galleria mellonella infection model. Survival curves of the larvae infected with CR-hvKP strains are shown in comparison with the high-virulence control strain NTUH-K2044, low-virulence control strain ATCC 700603, and PBS control. Statistical significance was determined by the log-rank (Mantel-Cox) test.

    Article Snippet: In contrast, the high-virulence control strain NTUH-K2044 showed a slightly lower LDH release (1.33 ± 0.05 μmol/L), while the low-virulence strain ATCC 700603 exhibited markedly reduced cytotoxicity (0.35 ± 0.03 μmol/L) with a significant difference compared to all other groups ( P < 0.0001).

    Techniques: Infection, Comparison, Control